1185993-10-5Relevant academic research and scientific papers
A mild, highly efficient, and chemoselective deprotection of trityl ethers of carbohydrates and nucleosides using iodine monobromide
Malik, Satish,Kartha, K. P. Ravindranathan
, p. 1809 - 1811 (2009)
Iodine monobromide in dichloromethane-methanol or acetonitrile constitutes an effective reagent for the deprotection of O-trityl and O-dimethoxytrityl ethers of carbohydrates and nucleosides. Acid-labile functionalities (acetals, O-p-methoxybenzyl ethers, etc.) as well as base-labile groups (esters and amides) are stable under these conditions; and the method has been found to be superior to the hitherto known literature methods. Georg Thieme Verlag Stuttgart.
