1186048-65-6

Basic information

• Product Name: 4-(4-iodophenyl)-1-[(4-nitroimidazol-1-yl)acetyl]thiosemicarbazide
• CAS NO: 1186048-65-6
• Molecular Weight: 446.228
• Mol File: 1186048-65-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-iodophenyl)-1-[(4-nitroimidazol-1-yl)acetyl]thiosemicarbazide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-iodophenyl)-1-[(4-nitroimidazol-1-yl)acetyl]thiosemicarbazide(1186048-65-6)
• EPA Substance Registry System: 4-(4-iodophenyl)-1-[(4-nitroimidazol-1-yl)acetyl]thiosemicarbazide(1186048-65-6)

Safety Data

• Hazardous Substances Data: 1186048-65-6(Hazardous Substances Data)

Upstream product

• 2059-76-9 4-iodophenyl isothiocyanate 
• 93637-75-3 (4-nitroimidazol-1-yl)acetic acid hydrazide 

Relevant articles and documents

New Derivatives of Thiosemicarbazide and 1,2,4-Triazoline-5-thione with Potential Antimicrobial Activity

In the reaction of the hydrazide of (4-nitroimidazol-1-yl)acetic acid 1 with isothiocyanates, the respective thiosemicarbazide derivatives 2-6 were obtained. Further cyclization with 2% NaOH led to the formation of 3-[(4-nitroimidazol-1-yl)-methyl]-4-substituted-1,2,4-triazoline-5-thiones 7-11. The structures of all new products were confirmed by analytical and spectroscopic methods. Six compounds 2-5, 8, and 10 were screened for their in vitro activity against some species of aerobic bacteria and fungi. Compound 3 appears to be a promising precursor of agents with antibacterial activity against Micrococcus luteus.