118617-57-5Relevant articles and documents
Asmic: An Exceptional Building Block for Isocyanide Alkylations
Alwedi, Embarek,Lujan-Montelongo, J. Armando,Pitta, Bhaskar R.,Chao, Allen,Cortés-Mejía, Rodrigo,Del Campo, Jorge M.,Fleming, Fraser F.
, p. 5910 - 5913 (2018)
Asmic addresses the long-standing challenge of alkylating isocyanides, providing access to isocyanides with diverse substitution patterns. The o-anisylsulfanyl group serves a critical dual role by facilitating deprotonation-alkylation and providing a latent nucleophilic site through an unusual arylsulfanyl-lithium exchange.
COMPOSITION, SYNTHESIS, AND USE OF A NEW CLASS OF ISONITRILES
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Paragraph 0050, (2015/09/23)
This invention relates to novel isonitriles, including arylthio isonitriles, and methods for their preparation. The isonitriles include a conjugated ring system. The structure is designed with the flexibility to have multiple substitution patterns. The isonitriles may be used in applications including, but not limited to, pharmaceutical compositions.
