1186191-30-9

Upstream product

• 40059-53-8 ethyl 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylate 
• 1186188-43-1 ethyl 3-methoxy-1-methyl-4-oxo-5-(2-oxo-2-phenylethyl)-4,5-dihydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylate 
• 1186188-42-0 ethyl 3-hydroxy-1-methyl-4-oxo-5-(2-oxo-2-phenylethyl)-4,5-dihydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylate 
• 1186188-41-9 ethyl 4-[(2-ethoxy-2-oxoethyl)(methyl)amino]-2-oxo-1-(2-oxo-2-phenylethyl)-1,2-dihydroquinoline-3-carboxylate 
• 99429-64-8 ethyl ester of 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylic acid 
• 27578-60-5 1-(2-aminoethyl)piperidine 
• 1186188-44-2 3-methoxy-1-methyl-4-oxo-5-(2-oxo-2-phenylethyl)-4,5-dihydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylic acid 

Relevant academic research and scientific papers

Discovery of pyrrolo[3,2-c]quinoline-4-one derivatives as novel hedgehog signaling inhibitors

The Hedgehog (Hh) signaling pathway plays a significant role in the regulation of cell growth and differentiation during embryonic development. Since activation of the Hh signaling pathway is implicated in several types of human cancers, inhibitors of thi

FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF

The present invention provides a compound having a superior Smo inhibitory activity and lower toxicity, which is sufficiently satisfactory as a pharmaceutical product. The present invention provides a compound represented by the formula wherein ring A is