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1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid ethyl ester is a chemical compound with the molecular formula C13H11NO4. It is an ethyl ester derivative of quinolinecarboxylic acid, characterized by its yellow crystalline solid form and solubility in organic solvents. 1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid ethyl ester serves as a versatile intermediate in the synthesis of pharmaceuticals and other organic compounds, and exhibits potential biological and pharmacological activities, including anti-inflammatory, antioxidant, and antimicrobial properties. It is also utilized as a building block in the production of medicinal drugs and agrochemicals.

40059-53-8

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40059-53-8 Usage

Uses

Used in Pharmaceutical Synthesis:
1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid ethyl ester is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new medicinal compounds with potential therapeutic applications.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, 1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid ethyl ester is used as a key component in the synthesis of other organic compounds, leveraging its reactivity and structural features to create a diverse range of products.
Used in Medicinal Drug Production:
As a building block, 1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid ethyl ester is used in the production of medicinal drugs, where its biological and pharmacological properties can be harnessed to develop effective treatments for various health conditions.
Used in Agrochemicals Production:
1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid ethyl ester also finds application in the agrochemical industry, where it is used as a building block for the development of agrochemicals, potentially contributing to crop protection and enhancement of agricultural yields.
Used in Research and Development:
1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid ethyl ester is utilized in research and development settings to explore its anti-inflammatory, antioxidant, and antimicrobial properties, with the aim of discovering new applications in medicine and other fields.

Check Digit Verification of cas no

The CAS Registry Mumber 40059-53-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,5 and 9 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 40059-53:
(7*4)+(6*0)+(5*0)+(4*5)+(3*9)+(2*5)+(1*3)=88
88 % 10 = 8
So 40059-53-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO4/c1-2-17-12(16)9-10(14)7-5-3-4-6-8(7)13-11(9)15/h3-6H,2H2,1H3,(H2,13,14,15)

40059-53-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 4-hydroxy-2-oxo-1H-quinoline-3-carboxylate

1.2 Other means of identification

Product number -
Other names 3-Carbethoxy-4-hydroxy-2-quinolone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40059-53-8 SDS

40059-53-8Relevant academic research and scientific papers

The laccase-catalyzed domino reaction between catechols and heterocyclic 1,3-dicarbonyls and theunambiguous structure elucidation of the products by NMR spectroscopy and X-ray crystal structure analysis

Hajdok, Szilvia,Conrad, Juergen,Leutbecher, Heiko,Strobel, Sabine,Schleid, Thomas,Beifuss, Uwe

body text, p. 7230 - 7237 (2010/01/16)

(Chemical Equation Presented) The laccase-catalyzed reaction between catechols and heterocyclic 1,3-dicarbonyls (pyridinones, quinolinones, thiocoumarins) using aerial oxygen as the oxidant delivers benzofuropyridinones, benzofuroquinolinones, and thiocou

4-hydroxy-2-quinolones 125. Ethyl 3-bromo-2,4-dioxo-1,2,3,4- tetrahydroquinoline-3-carboxylates as potential brominating agents

Ukrainets,Sidorenko,Golovchenko

, p. 1008 - 1013 (2008/09/19)

The spatial structural features of 3-bromo-3-ethoxycarbonyl-2,4-dioxo-1,2, 3,4-tetrahydroquinolines have been studied by X-ray analysis. It has been experimentally confirmed that these compounds can be regarded as potential brominating agents.

Alkylidenephosphoranes in heterocyclic synthesis: Reactivity of benzoxazinones with resonance-stabilized phosphorus ylides

Kamel, Azza A.,Abdou, Wafaa M.

, p. 1269 - 1273 (2007/12/27)

2H-3,1-Benzoxazine-2,4(1H)-dione and its N-methyl analogue react with alkylidenephosphoranes to give substituted quinolines and benzazepines as well as indanone and furan derivatives. Reaction mechanisms to explain the formation of products obtained are outlined. Georg Thieme Verlag Stuttgart.

4-hydroxy-2-quinolones. 30. Alkylation of 1H-2-oxo-3-carbethoxy-4-hydroxyquinoline

Ukrainets,Taran,Gorokhova,Gorlacheva,Bezuglyi,Turov

, p. 952 - 959 (2007/10/03)

A study has been made of the alkylation of 1H-2-oxo-3-carbethoxy-4-hydroxyquinoline by alkyl halides in the presence of inorganic bases. New methods for the synthesis of 1-substituted 2-oxo-3-carbethoxy-4-hydroxyquinolines are examined. 1997 Plenum Publishing Corporation.

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