118630-19-6

Basic information

• Product Name: 5-(4-PHENYLPIPERAZINO)-1H-1,2,4-TRIAZOL-3-AMINE
• Synonyms: 5-(4-PHENYLPIPERAZINO)-1H-1,2,4-TRIAZOL-3-AMINE;5-(4-PHENYLPIPERAZINO)-1H-1,2,4-TRIAZOL-3-YLAMINE
• CAS NO: 118630-19-6
• Molecular Formula: C12H16N6
• Molecular Weight: 244.3
• Mol File: 118630-19-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(4-PHENYLPIPERAZINO)-1H-1,2,4-TRIAZOL-3-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-PHENYLPIPERAZINO)-1H-1,2,4-TRIAZOL-3-AMINE(118630-19-6)
• EPA Substance Registry System: 5-(4-PHENYLPIPERAZINO)-1H-1,2,4-TRIAZOL-3-AMINE(118630-19-6)

Safety Data

• Hazardous Substances Data: 118630-19-6(Hazardous Substances Data)

Upstream product

• 92-54-6 4-phenyl-1-piperazine 
• 86123-51-5 N-Cyan-4-phenyl-1-piperazinthiocarbimidsaeure-methylester 

Relevant articles and documents

5-(1-Piperazinyl)-1H-1,2,4-triazol-3-amines as antihypertensive agents

A series of 5-(1-piperazinyl)-1H-1,2,4-triazol-3-amines was synthesized and screened for antihypertensive and diuretic activity in spontaneously hypertensive rats (SHR). One compound, 5-[4-[(3-chlorophenyl)methyl]-1-piperazinyl]-1H-1,2,4-triazol-3-amine (8), was selected to define the mechanism of its antihypertensive activity. Studies in SHR suggest ganglionic blocking activity. Short-lived antihypertensive activity was observed in conscious renal hypertensive dogs.