118630-33-4 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-CHLORO-4-FLUORO-BENZYL)-PIPERAZINE is used as a chemical intermediate for the synthesis of various pharmaceuticals and drugs. Its unique structure and properties make it a valuable component in the development of new medications with diverse therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-(2-CHLORO-4-FLUORO-BENZYL)-PIPERAZINE is employed as a starting material for the design and synthesis of novel compounds with potential biological activities. Its versatility allows for the exploration of various chemical modifications, leading to the discovery of new therapeutic agents.
Used in Drug Development:
1-(2-CHLORO-4-FLUORO-BENZYL)-PIPERAZINE is utilized in drug development as a scaffold for the creation of potential therapeutic agents. Its interesting biological activities and chemical properties make it a promising candidate for further research and development into new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 118630-33-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,6,3 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 118630-33:
(8*1)+(7*1)+(6*8)+(5*6)+(4*3)+(3*0)+(2*3)+(1*3)=114
114 % 10 = 4
So 118630-33-4 is a valid CAS Registry Number.
118630-33-4Relevant academic research and scientific papers
INHIBITORS OF STEAROYL-COA DESATURASE
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, (2009/06/27)
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity.
5-(1-Piperazinyl)-1H-1,2,4-triazol-3-amines as antihypertensive agents
Meyer,Tomcufcik,Chan,Haug
, p. 593 - 597 (2007/10/02)
A series of 5-(1-piperazinyl)-1H-1,2,4-triazol-3-amines was synthesized and screened for antihypertensive and diuretic activity in spontaneously hypertensive rats (SHR). One compound, 5-[4-[(3-chlorophenyl)methyl]-1-piperazinyl]-1H-1,2,4-triazol-3-amine (8), was selected to define the mechanism of its antihypertensive activity. Studies in SHR suggest ganglionic blocking activity. Short-lived antihypertensive activity was observed in conscious renal hypertensive dogs.
