1186388-89-5Relevant academic research and scientific papers
Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations
Kasper, Amanda C.,Moon, Eui Jung,Hu, Xiangqian,Park, Yongho,Wooten, Ceshea M.,Kim, Hyoungsu,Yang, Weitao,Dewhirst, Mark W.,Hong, Jiyong
, p. 3783 - 3786 (2009)
We have shown that manassantin A downregulated the HIF-1α expression and inhibited the secretion of VEGF. We have also demonstrated that the 2,3-cis-3,4-trans-4,5-cis-configuration of the tetrahydrofuran is critical to the HIF-1 inhibition of manassantin
MANASSANTIN COMPOUNDS AND METHODS OF MAKING AND USING SAME
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Page/Page column 42-43, (2010/07/10)
Provided are manassantin compounds and methods of using the compounds. Provided are methods of treating a disease, the method comprising administering a compound according to Formula I. Further provided are pharmaceutical compositions comprising compounds
