1186423-65-3Relevant academic research and scientific papers
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors
Swarbrick, Martin E.,Beswick, Paul J.,Gleave, Robert J.,Green, Richard H.,Bingham, Sharon,Bountra, Chas,Carter, Malcolm C.,Chambers, Laura J.,Chessell, Iain P.,Clayton, Nick M.,Collins, Sue D.,Corfield, John A.,Hartley, C. David,Kleanthous, Savvas,Lambeth, Paul F.,Lucas, Fiona S.,Mathews, Neil,Naylor, Alan,Page, Lee W.,Payne, Jeremy J.,Pegg, Neil A.,Price, Helen S.,Skidmore, John,Stevens, Alexander J.,Stocker, Richard,Stratton, Sharon C.,Stuart, Alastair J.,Wiseman, Joanne O.
scheme or table, p. 4504 - 4508 (2010/04/05)
A novel series of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidine-based cyclooxygenase-2 (COX-2) inhibitors, which have a different arrangement of substituents compared to the more common 1,2-diarylheterocycle based molecules, have been dis
