1186428-76-1

Basic information

• Product Name: 1-cyclohexyl-4-methylpentan-2-ol
• Synonyms: 1-cyclohexyl-4-methylpentan-2-ol
• CAS NO: 1186428-76-1
• Molecular Weight: 184.322
• Mol File: 1186428-76-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-cyclohexyl-4-methylpentan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclohexyl-4-methylpentan-2-ol(1186428-76-1)
• EPA Substance Registry System: 1-cyclohexyl-4-methylpentan-2-ol(1186428-76-1)

Safety Data

• Hazardous Substances Data: 1186428-76-1(Hazardous Substances Data)

Upstream product

• 5349-62-2 4-Methyl-1-phenyl-2-pentanone 
• 2550-36-9 Cyclohexylmethyl bromide 
• 590-86-3 isovaleraldehyde 

Downstream Products

• 1151967-55-3 1-cyclohexyl-4-methylpentan-2-yl sulfamate 
• 1151967-65-5 4,4-dimethyl-6-(cyclohexylmethyl)tetrahydro-1,2,3-oxathiazine-2,2-dioxide 
• 1151967-63-3 4-(2-methylpropyl)-3-oxa-2-thia-1-azaspiro[5.5]undecane-2,2-dioxide 

Relevant articles and documents

Selective Hydrogenation and Hydrodeoxygenation of Aromatic Ketones to Cyclohexane Derivatives Using a Rh&at;SILP Catalyst

Rhodium nanoparticles immobilized on an acid-free triphenylphosphonium-based supported ionic liquid phase (Rh&at;SILP(Ph3-P-NTf2)) enabled the selective hydrogenation and hydrodeoxygenation of aromatic ketones. The flexible molecular approach used to assemble the individual catalyst components (SiO2, ionic liquid, nanoparticles) led to outstanding catalytic properties. In particular, intimate contact between the nanoparticles and the phosphonium ionic liquid is required for the deoxygenation reactivity. The Rh&at;SILP(Ph3-P-NTf2) catalyst was active for the hydrodeoxygenation of benzylic ketones under mild conditions, and the product distribution for non-benzylic ketones was controlled with high selectivity between the hydrogenated (alcohol) and hydrodeoxygenated (alkane) products by adjusting the reaction temperature. The versatile Rh&at;SILP(Ph3-P-NTf2) catalyst opens the way to the production of a wide range of high-value cyclohexane derivatives by the hydrogenation and/or hydrodeoxygenation of Friedel–Crafts acylation products and lignin-derived aromatic ketones.

Ligand-controlled, tunable silver-catalyzed C-H amination

The development of readily tunable and regioselective C-H functionalization reactions that operate solely through catalyst control remains a challenge in modern organic synthesis. Herein, we report that simple silver catalysts supported by common nitrogenated ligands can be used to tune a nitrene transfer reaction between two different types of C-H bonds. The results reported herein represent the first example of ligand-controlled and site-selective silver-promoted C-H amination.