1186608-83-2

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-5-nitro-1H-pyrazole is used as a building block for the synthesis of various biologically active compounds, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical field, 3-Bromo-5-nitro-1H-pyrazole serves as a key component in the creation of pesticides and other agrochemical products, enhancing crop protection and yield.
Used in Materials Science:
3-Bromo-5-nitro-1H-pyrazole is utilized as a reagent in organic synthesis, playing a role in the development of new materials with specific properties for various applications in science and industry.
Used in Research and Development:
This chemical compound is also used in research for its potential anti-inflammatory and analgesic properties, indicating its possible use in the development of medications for pain relief and inflammation management.

Upstream product

• 63572-73-6 5-nitropyrazolo<3,4-b>pyridine 

Downstream Products

• 1186607-36-2 N-(3-(1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluoro-3-(propylsulfonamido)benzamide 
• 1186609-91-5 5-nitro-N-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazolo[3,4-b]pyridin-3-amine 
• 1186608-94-5 N₃-phenyl-1H-pyrazolo[3,4-b]pyridine-3,5-diamine 
• 1616388-21-6 tert-butyl 4-[3-(5-nitro-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl]piperazine-1-carboxylate 
• 1616387-14-4 tert-butyl 4-[3-[5-[(3,4-dimethyl-1H-pyrazole-5-carbonyl)amino]-1H-pyrazolo[3,4-b]pyridin-3-yl]phenyl]piperazine-1-carboxylate 
• 1616388-22-7 tert-butyl 4-[3-(5-amino-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl]piperazine-1-carboxylate 
• 1616385-69-3 3,4-dimethyl-N-[3-(3-piperazin-1-ylphenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]-1H-pyrazole-5-carboxamide 

Relevant academic research and scientific papers

FIVE-AND-SIX-MEMBERED HETEROCYCLIC COMPOUND AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITOR

A class of five-membered fused with six-membered heterocyclic compounds represented by formula I and a pharmaceutical composition, preparation, and an application thereof are disclosed. These compounds have TRK kinase inhibitory activity and can treat diseases related to TRK dysfunction.

Methyl-1H-indazole ROR gamma conditioning agent and application thereof

The invention relates to a compound or a stereisomer, a tautomer or pharmaceutically acceptable salt or a solvate or a prodrug thereof, a preparation method thereof, a pharmaceutical composition containing the conditioning agents and application of the ph

1H-PYRAZOLO [3, 4-B] PYRIDINE COMPOUNDS FOR INHIBITING RAF KINASE

Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. [FORMULA I]

Pyrazolopyridine inhibitors of B-RafV600E. Part 1: The development of selective, orally bioavailable, and efficacious inhibitors

The V600E mutation of B-Raf kinase results in constitutive activation of the MAPK signaling pathway and is present in approximately 7% of all cancers. Using structure-based design, a novel series of pyrazolopyridine inhibitors of B-RafV600E was

PYRAZOLE [3, 4-B] PYRIDINE RAF INHIBITORS

Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.