1186621-76-0Relevant articles and documents
Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach: An alternative tool to discriminate between the human adenosine A2A and A3 receptor pyrazolo-triazolo-pyrimidine antagonists bi
Michielan, Lisa,Bolcato, Chiara,Federico, Stephanie,Cacciari, Barbara,Bacilieri, Magdalena,Klotz, Karl-Norbert,Kachler, Sonja,Pastorin, Giorgia,Cardin, Riccardo,Sperduti, Alessandro,Spalluto, Giampiero,Moro, Stefano
experimental part, p. 5259 - 5274 (2009/12/04)
G Protein-coupled receptors (GPCRs) selectivity is an important aspect of drug discovery process, and distinguishing between related receptor subtypes is often the key to therapeutic success. Nowadays, very few valuable computational tools are available f