1186650-22-5

Basic information

• Product Name: 5-fluoro-2-(4-fluorophenyl)benzo[d]isothiazol-3(2H)-one
• CAS NO: 1186650-22-5
• Molecular Weight: 263.267
• Mol File: 1186650-22-5.mol

Chemical Properties

• CAS DataBase Reference: 5-fluoro-2-(4-fluorophenyl)benzo[d]isothiazol-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluoro-2-(4-fluorophenyl)benzo[d]isothiazol-3(2H)-one(1186650-22-5)
• EPA Substance Registry System: 5-fluoro-2-(4-fluorophenyl)benzo[d]isothiazol-3(2H)-one(1186650-22-5)

Safety Data

• Hazardous Substances Data: 1186650-22-5(Hazardous Substances Data)

Upstream product

• 104456-81-7 methyl 5-fluoro-2-sulfanyl-benzoate 
• 371-40-4 4-fluoroaniline 

Relevant articles and documents

BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE

The disclosure provides new compounds and compositions thereof, and methods for treating or ameliorating a disorder relating to CDG-Ia. In particular, the disclosure provides benzoisothiazolone inhibitors of PMI, which have been synthesized and their abil

Potent, selective, and orally available benzoisothiazolone phosphomannose isomerase inhibitors as probes for congenital disorder of glycosylation Ia

We report the discovery and validation of a series of benzoisothiazolones as potent inhibitors of phosphomannose isomerase (PMI), an enzyme that converts mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) and, more importantly, competes wit