1186663-29-5 Usage
General Description
Ethyl 2-(Methylsulfonyl)nicotinate is a chemical compound with the molecular formula C10H13NO5S. It is an ester derivative of nicotinic acid, commonly known as vitamin B3. Ethyl 2-(Methylsulfonyl)nicotinate is commonly used in the pharmaceutical industry as a vasodilator, meaning it helps to widen blood vessels and improve blood flow. It has also been studied for its potential use in treating various cardiovascular diseases, including hypertension and angina. Additionally, it is reported to possess anti-inflammatory and antioxidant properties, making it a potentially valuable ingredient in skincare products. Overall, Ethyl 2-(Methylsulfonyl)nicotinate has a range of potential applications in the medical and cosmetic industries due to its vasodilatory, anti-inflammatory, and antioxidant effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1186663-29-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,6,6,6 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1186663-29:
(9*1)+(8*1)+(7*8)+(6*6)+(5*6)+(4*6)+(3*3)+(2*2)+(1*9)=185
185 % 10 = 5
So 1186663-29-5 is a valid CAS Registry Number.
1186663-29-5Relevant articles and documents
Nickel-Catalyzed Reductive 2-Pyridination of Aryl Iodides with Difluoromethyl 2-Pyridyl Sulfone
Miao, Wenjun,Ni, Chuanfa,Xiao, Pan,Jia, Rulong,Zhang, Wei,Hu, Jinbo
, p. 711 - 715 (2021)
A novel nickel-catalyzed reductive cross-coupling between aryl iodides and difluoromethyl 2-pyridyl sulfone (2-PySO2CF2H) enables C(sp2)-C(sp2) bond formation through selective C(sp2)-S bond cleavage, which demonstrates the new reactivity of 2-PySO2CF2H reagent. This method employs readily available nickel catalyst and sulfones as cross-electrophile coupling partners, providing facile access to biaryls under mild reaction conditions without pregeneration of arylmetal reagents.
