1187236-21-0

Basic information

• Product Name: IMidazo[1,2-a]pyridine-2-Methanol, 7-broMo-
• Synonyms: IMidazo[1,2-a]pyridine-2-Methanol, 7-broMo-;(7-BroMo-iMidazo[1,2-a]pyridin-2-yl)-Methanol;7-bromo-Imidazo[1,2-a]pyridine-2-methanol;(7-bromoimidazo[1,2-a]pyridin-2-yl)methanol(WX130150)
• CAS NO: 1187236-21-0
• Molecular Formula: C8H7BrN2O
• Molecular Weight: 227.05798
• Mol File: 1187236-21-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: IMidazo[1,2-a]pyridine-2-Methanol, 7-broMo-(CAS DataBase Reference)
• NIST Chemistry Reference: IMidazo[1,2-a]pyridine-2-Methanol, 7-broMo-(1187236-21-0)
• EPA Substance Registry System: IMidazo[1,2-a]pyridine-2-Methanol, 7-broMo-(1187236-21-0)

Safety Data

• Hazardous Substances Data: 1187236-21-0(Hazardous Substances Data)

Upstream product

• 84249-14-9 2-amino-4-bromopyridine 
• 1187236-18-5 7-bromoimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester 

Downstream Products

• 1019023-07-4 7-bromo-2-chloromethylimidazo[1,2-a]pyridine 
• 1454907-26-6 (4S,5R)-4-fluoromethyl-5-{4-[2-(methanesulfonylaminomethyl)imidazo[1,2-a]pyridin-7-yl]phenyl}-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 1454907-27-7 N-{7-[4-((1R,2S)-2-amino-3-fluoro-1-hydroxypropyl)phenyl]imidazo[1,2-a]pyridin-2-ylmethyl}methanesulfonamide 
• 1454904-55-2 2,2-difluoro-N-((1S,2R)-1-fluoromethyl-2-hydroxy-2-{4-[2-(methanesulfonylaminomethyl)imidazo[1,2-a]pyridin-7-yl]phenyl}ethyl)acetamide 

Relevant articles and documents

TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

The present disclosure relates to compounds which modulate the activity of Toll-like receptor (TLR) proteins, including agonists or activators, partial agonists, and antagonists. Of particular interest of compounds that modulate the activity of TLR2, as well as methods of using such compounds to treat cancer and other disorders associated with a TLR2 pathway.

3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR

The present invention is directed to pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

N-AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

This disclosure relates to compounds of formula (I): wherein X1, X2, X3, X4, n, Y, W, and A are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.