118736-10-0

Basic information

• Product Name: 2-hydroxy-2-(naphthalen-2-yl)-1-phenylethanone
• Synonyms: 2-hydroxy-2-(naphthalen-2-yl)-1-phenylethanone
• CAS NO: 118736-10-0
• Molecular Weight: 262.308
• Mol File: 118736-10-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-2-(naphthalen-2-yl)-1-phenylethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-2-(naphthalen-2-yl)-1-phenylethanone(118736-10-0)
• EPA Substance Registry System: 2-hydroxy-2-(naphthalen-2-yl)-1-phenylethanone(118736-10-0)

Safety Data

• Hazardous Substances Data: 118736-10-0(Hazardous Substances Data)

Upstream product

• 91-20-3 naphthalene 
• 1074-12-0 phenylglyoxal hydrate 
• 1051400-84-0 naphthalen-2-yl(2-phenyl-1,3-dithian-2-yl)methanol 

Downstream Products

• 65648-94-4 1-(naphthalen-2-yl)-2-phenylethane-1,2-dione 

Relevant articles and documents

Enantioselective monoreduction of different 1,2-diaryl-1,2-diketones catalysed by lyophilised whole cells from Pichia glucozyma

In this work we have studied the monoreduction of different 1,2-diaryl-ethanediones (benzils, 1) with lyophilised whole cells from Pichia glucozyma CBS 5766, using the diphenyl compound (benzil, 1a) as model substrate, and extended the enantioselective reduction to structurally different symmetric benzils for producing enantiomerically pure or enriched benzoins (α-hydroxyketones 2) in high yields and very short reaction times. In order to study the regio- and stereoselectivity of this biocatalyst, we examined the reduction of diaryldiketones formed from different aryl moieties, to obtain symmetric and asymmetric crossed-benzoins. This methodology is conducted under very mild reaction conditions (aqueous media with small amounts of DMSO for solubilising the substrates, T=28 °C), therefore constituting a green alternative compared to other reported procedures for obtaining homochiral benzoins.