1187363-41-2Relevant academic research and scientific papers
COMPOUNDS, THEIR SYNTHESES, COMPOSITIONS, AND METHODS TO TREAT CANCER
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Page/Page column 27, (2010/09/03)
Compounds and their syntheses are disclosed herein. Compositions and pharmaceutical compositions comprising a compound are also described, and include compositions also comprising liposomes. Methods for the treatment of cancer in animals comprising administering a compound or a composition comprising a compound are also described.
Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells
Antoon, James W.,Liu, Jiawang,Gestaut, Matthew M.,Burow, Matthew E.,Beckman, Barbara S.,Foroozesh, Maryam
experimental part, p. 5748 - 5752 (2010/03/24)
Resistance to chemotherapy and endocrine therapy is a major cause of breast cancer treatment failure. We have synthesized six novel analogues using C8-ceramide as the lead analogue and studied their effect on hormone therapy resistant (MDA-MB-231) and che
