118741-14-3

Upstream product

• 131116-20-6 (4S,5R)-3-benzyloxycarbonyl-4-cyclohexylmethyl-5-formyl-2,2-dimethyloxazolidine 
• 118741-13-2 (4S,5S)-3-benzyloxycarbonyl-4-cyclohexylmethyl-5-(2-ethoxycarbonyl-1-butenyl)-2,2-dimethyloxazolidine 
• 118741-29-0 N-benzyloxycarbonyl-L-cyclohexylalanine 3,5-dimethyl-pyrazolide 
• 118741-11-0 (4S,5RS)-3-benzyloxycarbonyl-L-cyclohexylmethyl-5-ethenyl-2,2-dimethyloxazolidine 
• 118741-09-6 (3RS,4S)-4-benzyloxycarbonyl-amino-5-cyclohexyl-3-hydroxy-1-pentene 
• 105852-47-9 2-<(benzyloxycarbonyl)amino>-3-cyclohexyl-(2S)-propionaldehyde 
• 78-81-9 isobutylamine 
• 118741-05-2 (4S,5S)-5-((E)-2-Carboxy-but-1-enyl)-4-cyclohexylmethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 

Downstream Products

• 141738-66-1 (2RS,4S,5S)-N-isobutyl-5--L-norleucyl>amino-6-cyclohexyl-2-ethyl-4-hydroxyhexanamide 
• 141713-98-6 {(S)-1-[(S)-1-((1S,2S)-1-Cyclohexylmethyl-2-hydroxy-4-isobutylcarbamoyl-hexylcarbamoyl)-pentylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Renin inhibitors. I. Synthesis and structure-activity relationship of transition-state inhibitors containing homostatine analogues at the scissile bond

The synthesis and structure-activity relationships of transition-state renin inhibitors containing the homostatine analogues at the scissile bond are described. These inhibitors incorporate the amino acid side chains corresponding to positions 7-12 (Psub

5-Substituted amino-4-hydroxy-pentenoic acid derivatives and their use

A 5-substituted amino-4-hydroxy-pentenoic acid or its salt represented by the formula: wherein each of R1 and R2 which may be the same or different is a hydrogen atom, a lower alkyl group, an aralkyl group, a lower alkoxycarbonyl group, an aryloxycarbonyl group, an aralkyloxycarbonyl group or a lower alkanoyl group which may be substituted by from one to three substituents selected from the group consisting of an amino group, a hydroxyl group, a carboxyl group, an aryloxy group, an aralkyloxycarbonylamino group, a lower alkoxycarbonylamino group and a group (wherein each of X1 and X2 which may be the same or different is a hydrogen atom, a lower alkyl group, an aryl group or an aralkyl group, or X1 and X2 form together with the adjacent nitrogen atom a 5- or 6-membered heterocyclic group which may further contain a hetero atom selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom) and which may further contain a double bond in its carbon chain, each of R3, R4 and R6 which may be the same or different is a hydrogen atom, a lower alkyl group, a cycloalkyl group, a cycloalkylalkyl group, an aryl group, an aralkyl group or a residue of an acidic, neutral or basic amino acid, R5 is a hydrogen atom or a lower alkyl group, R7 is a hydrogen atom, a lower alkyl, cycloalkyl, cycloalkylalkyl or aralkyl group which may be substituted by one or two hydroxyl groups or a residue of an acidic, neutral or basic amino acid, R8 is a hydroxyl group, a -OY group (wherein Y is a lower alkyl group, an aryl group, an aralkyl group, a lower alkoxyalkyl group, a lower alkanoyloxyalkyl group, a lower alkoxycarbonyloxyalkyl group, or a 1-phthalidyl group) or a group (wherein each of Y1 and Y2 which may be the same or different is a hydrogen atom, a lower alkyl group, an aryl group, an aralkyl group or a cycloalkyl group, or Y1 and Y2 form together with the adjacent nitrogen atom a 5- or 6-membered heterocyclic group which may further contain a hetero atom selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom), and each of n and m which may be the same or different is 0 or 1.