118741-50-7Relevant academic research and scientific papers
Rhenium-catalyzed aromatic propargylation
Kennedy-Smith, Joshua J.,Young, Lauren A.,Toste, F. Dean
, p. 1325 - 1327 (2007/10/03)
A mild aromatic propargylation reaction, employing an air- and moisture-tolerant rhenium-oxo complex ((dppm)ReOCl3) as a catalyst and a propargyl alcohol as the electrophile, is described. The reaction tolerates a broad range of functional groups and regioselectively affords propargylic arenas without formation of the isomeric allenyl adducts. The potential of this rhenium(V)-catalyzed reaction is exemplified by application of the propargylation to the synthesis of O-methyldetrol, mimosifoliol, and β-apopicropodophyllin.
Propiolophenone derivatives
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, (2008/06/13)
Propiolophenone derivatives of the formula STR1 wherein R6 is hydrogen, lower alkyl or a group of the formula STR2 as well as corresponding hydroxy compounds of the formula STR3 wherein R6' is hydrogen, lower alkyl, a group of formula (a), (b), (c), (d) or (e) or a group of the formula exhibit mucosa-protective and/or gastric acid secretion-inhibiting properties, such that they can be used for the control or prevention of illnesses of the gastrointestinal tract, especially against gastric ulcers and/or duodenal ulcers.
