1187451-02-0

Basic information

• Product Name: tert-butyl (tert-butoxycarbonyl{6-[(4-bromobenzyl)(pyridin-2-yl-sulfonyl)aminomethyl]pyridin-2-yl}amino)acetate
• Synonyms: tert-butyl (tert-butoxycarbonyl{6-[(4-bromobenzyl)(pyridin-2-yl-sulfonyl)aminomethyl]pyridin-2-yl}amino)acetate
• CAS NO: 1187451-02-0
• Molecular Weight: 647.59
• Mol File: 1187451-02-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: tert-butyl (tert-butoxycarbonyl{6-[(4-bromobenzyl)(pyridin-2-yl-sulfonyl)aminomethyl]pyridin-2-yl}amino)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (tert-butoxycarbonyl{6-[(4-bromobenzyl)(pyridin-2-yl-sulfonyl)aminomethyl]pyridin-2-yl}amino)acetate(1187451-02-0)
• EPA Substance Registry System: tert-butyl (tert-butoxycarbonyl{6-[(4-bromobenzyl)(pyridin-2-yl-sulfonyl)aminomethyl]pyridin-2-yl}amino)acetate(1187451-02-0)

Safety Data

• Hazardous Substances Data: 1187451-02-0(Hazardous Substances Data)

Upstream product

• 1187451-25-7 tert-butyl [tert-butoxycarbonyl(6-ethoxycarbonylpyridine-2-yl)amino]acetate 
• 1187450-49-2 tert-butyl (tert-butoxycarbonyl(6-(hydroxymethyl)pyridin-2-yl)amino)acetate 
• 1313217-74-1 N-(4-bromobenzyl)pyridin-2-ylsulfonamide 
• 203321-86-2 6-tert-butoxycarbonylamino-pyridine-2-carboxylic acid ethyl ester 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 66715-65-9 pyridine-2-sulfonyl chloride 
• 1187450-89-0 tert-butyl (tert-butoxycarbonyl{6-[(pyridin-2-ylsulfonyl)aminomethyl]pyridin-2-yl}amino)acetate 
• 589-15-1 1-bromomethyl-4-bromobenzene 

Downstream Products

• 1187451-03-1 tert-butyl [tert-butoxycarbonyl(6-{(pyridin-2-ylsulfonyl)[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzyl]aminomethyl}pyridin-2-yl)amino]acetate 
• 1273386-42-7 tert-butyl [tert-butoxycarbonyl(6-{[4-(phenylamino)benzyl](pyridin-2-ylsulfonyl)aminomethyl}pyridin-2-yl)amino]acetate 
• 1273386-28-9 (6-{[4-(phenylamino)benzyl](pyridin-2-ylsulfonyl)amino methyl}pyridin-2-ylamino)acetic acid 
• 1313216-88-4 tert-butyl ({6-[(4-acetylbenzyl)(pyridin-2-ylsulfonyl)aminomethyl]pyridin-2-yl}tert-butoxycarbonylamino)acetate 
• 1313216-41-9 (6-{[4-(1-methyl-1-pentenyl)benzyl](pyridin-2-ylsulfonyl)aminomethyl}pyridin-2-ylamino)acetic acid 
• 1313216-89-5 tert-butyl [tert-butoxycarbonyl(6-{[4-(1-methyl-1-pentenyl)benzyl](pyridin-2-ylsulfonyl)aminomethyl}pyridin-2-yl)amino]acetate 
• 1187451-04-2 tert-butyl [tert-butoxycarbonyl(6-{[4-(5-methylthiazol-2-yl)benzyl](pyridin-2-ylsulfonyl)aminomethyl}pyridin-2-yl)amino]acetate 

Relevant articles and documents

SUBSTITUTED BIARYL COMPOUND

The present invention provides a substituted biaryl compound of general formula (I): wherein, R1, W, R2, and Z are as defined in the claims and the description, or a pharmacologically acceptable salt thereof. The compound according to the present invention has an excellent inhibition effect of pulmonary fibroblast proliferation, and is therefore useful as a therapeutic agent and/or a prophylactic agent for interstitial pneumonia and pulmonary fibrosis.

AMINOPYRIDINE COMPOUND

The present invention relates to a compound represented by the formula (I): or a pharmaceutically acceptable salt thereof, a medical composition containing the same, and a medical composition for the treatment or prophylaxis of respiratory diseases or glaucoma.

PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA

The present invention is to provide a medical composition for the treatment or prophylaxis of glaucoma which comprises a pyridylaminoacetic acid compound represented by the formula (1): wherein R1, R2 and R3 each independe