1187461-93-3Relevant academic research and scientific papers
Reductive and brominative termination of alkenol cyclization in aerobic cobalt-catalyzed reactions
Schuch, Dominik,Fries, Patrick,Doenges, Maike,Perez, Barbara Menendez,Hartung, Jens
supporting information; experimental part, p. 12918 - 12920 (2009/12/05)
(Chemical Equation Presented) Tetrahydrofur-2-ylmethyl radicals were stereoselectively generated from substituted pent-4-en-1-ols in aerobic cobalt(II)-catalyzed oxidations. Intermediates were trapped with cyclohexa -1,4-diene, γ-terpinene, BrCCl3, diethyl dibromomalonate, or electron-deficient olefins such as acrylonitrile or dimethyl fumarate to afford functionalized tetrahydrofurans in synthetically useful yields.
