118754-52-2

Basic information

• Product Name: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde
• Synonyms: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde
• CAS NO: 118754-52-2
• Molecular Formula: C₈H₃Cl₂F₃O
• Molecular Weight: 243.0100296
• Mol File: 118754-52-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde(118754-52-2)
• EPA Substance Registry System: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde(118754-52-2)

Safety Data

• Hazardous Substances Data: 118754-52-2(Hazardous Substances Data)

Usage

General Description

2,6-Dichloro-4-trifluoroMethyl-benzaldehyde is a chemical compound with the molecular formula C8H4Cl2F3O. It is an aromatic aldehyde with two chlorine atoms and three trifluoromethyl groups attached to a benzene ring. 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde is used in organic synthesis and in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. It can also be used as an intermediate in the synthesis of other organic compounds. 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde is a highly reactive compound and should be handled and stored with care due to its potential hazards.

Upstream product

• 54773-20-5 1,3-dichloro-5-(trifluoromethyl)benzene 
• 68-12-2 N,N-dimethyl-formamide 
• 118754-53-3 2-bromo-1,3-dichloro-5-(trifluoromethyl)benzene 
• 2591-86-8 N-Formylpiperidine 

Downstream Products

• 118754-34-0 2-(2,6-dichloro-4-trifluoromethylphenyl)-4-methylimidazole 
• 118754-23-7 D-2-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylimidazole 
• 1415130-47-0 ethyl 3-(5-(3-chloro-2-formyl-5-(trifluoromethyl)phenyl)picolinamido)propanoate 
• 1414931-81-9 ethyl 3-(2'-(((2-chloro-2'-methyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)amino)methyl)-3'-isopropyl-5'-(trifluoromethyl)-[1,1'-biphenyl]-4-ylcarboxamido)propanoate 
• 1414931-43-3 3-(2'-(((2-chloro-2'-methyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)amino)methyl)-3'-isopropyl-5'-(trifluoromethyl)-[1,1'-biphenyl]-4-ylcarboxamido)propanoic acid 
• 1414931-76-2 Methyl 3'-chloro-2'-formyl-5'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate 

Relevant articles and documents

BIPHENYL DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS

The present invention is directed to biphenyl derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.

CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS

The present invention relates to the use of a compound of general formula (I) wherein R1/R2 are independently from each other hydrogen, lower alkyl, -CH2)o-cycloalkyl for o being 0 or 1, or are benzyl or heterocycloalkyl; or R1 and R2 are together with the N-atom to which they are attached a ring containing -(CH2)3-, -(CH2)4-, -(CH2)5-, -(CH2)2-O-(CH2)2-, -(CH2)2-S-(CH2)2-, -(CH2)2-NR-(CH2)2-, -(CH2)2-C(O)-(CH2)2-, -(CH2)2-CF2-(CH2)2-, -CH2-CHR-(CH2)2, -CHR-(CH2)3, CHR-(CH2)2-CHR-, or is the ring 2,6-diaza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester and R is hydroxy, halogen, cycloalkyl, or C(O)O-lower alkyl; X is -(CH2)4-, -(CH2)3-, -(CH2)2- or -CH2-; R3 is S-lower alkyl, CF3, OCHF2, lower alkoxy, lower alkyl, phenyl, cycloalkyl or halogen; R4 is CF3, lower alkoxy, lower alkyl, halogen and n is 1 or 2; or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomers and/or optical isomers thereof for the manufacture of a medicament for the treatment of psychoses, pain, dysfunction in memory and learning, attention deficit, schizophrenia, dementia disorders or Alzheimer's disease.

Pesticidal method using 2-phenylimidazole derivatives

The invention provides a method for the control of arthropod, plant nematode, helminth or protozoan pests using a 2-phenylimidazole derivative of the formula: STR1 wherein R1 represents hydrogen, alkyl (optionally substituted by alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, carboxy or alkoxycarbonyl), R2 and R3, each represents hydrogen, halogen, nitro, carboxy, cyano, alkoxycarbonyl, alkanoyl, or optionally alkyl substituted carbamoyl or sulphamoyl, or amino (optionally substituted by alkyl, alkoxycarbonyl or alkanoyl) or a group R, RO, RS, RSO or RSO2 in which R represents alkyl (optionally substituted by halogen), and Ar represents a group of the formula: STR2 wherein R4 and R6 each represents halogen or a group R, RO, RS, RSO or RSO2, and R5, R7 and R8 each represents a substituent as defined for R4 and R6, or represents hydrogen, hydroxy, carboxy, nitro, cyano, amino, alkylamino (optionally substituted by alkyl, alkoxycarbonyl or alkanoyl), alkoxycarbonyl or alkanoyl or a pesticidally acceptable salt thereof, with the exclusion of compounds in which R2 and R3 simultaneously represent hydrogen atoms, compositions for use in the method and novel compounds of formula I.