1187634-76-9Relevant academic research and scientific papers
Novel, achiral aminoheterocycles as selective monoamine reuptake inhibitors
Lucas, Matthew C.,Carter, David S.,Cai, Hai-Ying,Lee, Eun Kyung,Schoenfeld, Ryan C.,Steiner, Sandra,Villa, Marzia,Weikert, Robert J.,Iyer, Pravin S.
scheme or table, p. 4630 - 4633 (2010/04/30)
A variety of novel aminoheterocycle scaffolds as selective monoamine reuptake inhibitors have been prepared and one of these scaffolds is achiral. The main elements responsible for hERG channel, CYP2D6 and CYP3A4 inhibition were identified.
