1189121-76-3Relevant academic research and scientific papers
Novel, achiral aminoheterocycles as selective monoamine reuptake inhibitors
Lucas, Matthew C.,Carter, David S.,Cai, Hai-Ying,Lee, Eun Kyung,Schoenfeld, Ryan C.,Steiner, Sandra,Villa, Marzia,Weikert, Robert J.,Iyer, Pravin S.
scheme or table, p. 4630 - 4633 (2010/04/30)
A variety of novel aminoheterocycle scaffolds as selective monoamine reuptake inhibitors have been prepared and one of these scaffolds is achiral. The main elements responsible for hERG channel, CYP2D6 and CYP3A4 inhibition were identified.
AMINOPIPERIDINYL DERIVATIVES AND USES THEREOF
-
Page/Page column 38, (2009/10/06)
This application discloses aminopiperidinyl compounds of generic Formulae I-II: or pharmaceutically acceptable salts thereof, wherein m, r, Q1, Q2, Q3, R, Ra, R1, R2a, R2b, and R3 are defined as described herein, useful for treatment of diseases associated with monoamine reuptake inhibitors. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
