1187652-41-0Relevant academic research and scientific papers
2-Arylmethylaminomethyl-5,6-dihydroxychromone derivatives with selective anti-HCV activity
Park, Hye Ri,Park, Kwang-Su,Chong, Youhoon
scheme or table, p. 3202 - 3205 (2011/07/07)
Anti-HCV activity of aryl diketoacid (ADK) has been characterized by its two pharmacophoric elements, α,β-diketo acid moiety and substituted aryl ring. In this study, as a part of our ongoing efforts to discover a novel anti-HCV compound mimicking the ADK
Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives
Lee, Chaewoon,Lee, Jin Moo,Lee, Na-Ra,Kim, Dong-Eun,Jeong, Yong-Joo,Chong, Youhoon
experimental part, p. 4538 - 4541 (2010/04/03)
Aryl diketoacids have been identified as the first SARS-CoV NTPase/helicase inhibitors with a distinct pharmacophore featuring an arylmethyl group attached to a diketoacid. In order to search for the pharmacophore space around the diketoacid core, three c
