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1187660-29-2

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1187660-29-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1187660-29-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,7,6,6 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1187660-29:
(9*1)+(8*1)+(7*8)+(6*7)+(5*6)+(4*6)+(3*0)+(2*2)+(1*9)=182
182 % 10 = 2
So 1187660-29-2 is a valid CAS Registry Number.

1187660-29-2Relevant articles and documents

4-ARYL-2-ANILINO-PYRIMIDINES AS PLK KINASE INHIBITORS

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, (2009/10/22)

The present invention relates to compounds of Formula (Ia) or (Ib), the N-oxide forms, pharmaceutically acceptable addition salts, quaternary amines, stereoisomers, tautomers, racemics, metabolites, prodrugs, hydrates, or solvates thereof, wherein Y1, m, n, R1; X1; X2; R2; X3; X4; R3; and R4 have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to compounds that are kinase inhibitors useful for the treatment of disease states mediated by kinase, especially PLK4, in particular such compounds that are useful in the treatment of pathological processes which involve an aberrant cellular proliferation, such as tumor growth, rheumatoid arthritis, restenosis and atherosclerosis.

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