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4-(4-chlorophenyl)-N-(4-(2-cyclopropylpyrazolo[1,5-a]pyrimidin-7-ylthio)phenyl)phthalazin-1-amine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1187875-70-2

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1187875-70-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1187875-70-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,7,8,7 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1187875-70:
(9*1)+(8*1)+(7*8)+(6*7)+(5*8)+(4*7)+(3*5)+(2*7)+(1*0)=212
212 % 10 = 2
So 1187875-70-2 is a valid CAS Registry Number.

1187875-70-2Downstream Products

1187875-70-2Relevant academic research and scientific papers

AURORA KINASE MODULATORS AND METHOD OF USE

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, (2009/10/22)

The present invention relates to chemical compounds having a general formula (I) wherein A1-5 and 7-8, D', L1, L2, R1, R3, R6-8, n and o are defined herein, and synthetic intermediates, which are capable of modulating the activity of Aurora kinase proteins and, thereby, influencing various disease states and conditions related to the activities of Aurora kinases. For example, the compounds are capable of influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of Aurora kinase.

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