118793-50-3Relevant academic research and scientific papers
Handy Protocols using Vinyl Nosylates in Suzuki-Miyaura Cross-Coupling Reactions
Dikova, Anna,Cheval, Nicolas P.,Blanc, Aurélien,Weibel, Jean-Marc,Pale, Patrick
, p. 4093 - 4100 (2016/01/25)
Vinyl nosylates derived from 1,3-dicarbonyl compounds could be engaged in Suzuki-Myaura cross coupling reactions with aryl-, vinyl- and methylboronic acids or trifluoborate derivatives at room temperature in the presence of 2mol% of [1,1′-bis(diphenylphosphino)ferrocene]dichloropalladium(II) [PdCl2(dppf)]. One-pot procedures have been set up for practical and efficient nosylation-cross-coupling reactions. Nosylate, as a cheap novel pseudo-halide, gives very stable compounds and is very efficient in Suzuki-Myaura cross coupling reactions (21 examples, 44-99%).
[Pd(PPh3)2 (saccharinate)2]- general catalyst for Suzuki-Miyaura, Negishi cross-coupling and C-H bond functionalization of coumaryl and pyrone substrates
Shah, Parin,Santana, M. Dolores,García, Joaquín,Serrano, J. Luis,Naik, Minal,Pednekar, Suhas,Kapdi, Anant R.
supporting information, p. 1446 - 1453 (2013/02/25)
The potential of complex [Pd(PPh3)2(saccharinate) 2] 1 in catalyzing Suzuki-Miyaura cross-coupling of 4-halo and 4-bromomethyl coumaryl and pyrone substrates with different aryl boronic acids has been explored. Excellent yields of the desired products are obtained in competitive reaction time and under relatively mild conditions. Negishi cross-coupling of 4-coumaryl tosylate with aryl and alkylzinc reagents has also been performed with good yields of the cross-coupled products obtained in most cases. Intra-molecular C-H bond functionalization of coumaryl ethers also furnished very high yields of synthetically attractive tetracyclic ring systems exhibiting the potential of 1 as a powerful catalyst in synthetically important reactions.
Synthesis of 4-Alkylcoumarins
Patra, Amarendra,Misra, Swapan K.
, p. 272 - 273 (2007/10/02)
Grignard addition of appropriated alkylmagnesium halides to 3-carbethoxycoumarin (1) in the presence of cuprous bromide followed by hydrolysis, decarboxylation and subsequent dehydrogenation of the resulting dihydrocoumarins (3) affords 4-alkylcoumarins.
