1187943-46-9

Basic information

• Product Name: 5-[N-benzyl-N-(4-methoxybenzyl)amino]-4-bromo-2-phenylpentanenitrile
• CAS NO: 1187943-46-9
• Molecular Weight: 463.417
• Mol File: 1187943-46-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[N-benzyl-N-(4-methoxybenzyl)amino]-4-bromo-2-phenylpentanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[N-benzyl-N-(4-methoxybenzyl)amino]-4-bromo-2-phenylpentanenitrile(1187943-46-9)
• EPA Substance Registry System: 5-[N-benzyl-N-(4-methoxybenzyl)amino]-4-bromo-2-phenylpentanenitrile(1187943-46-9)

Safety Data

• Hazardous Substances Data: 1187943-46-9(Hazardous Substances Data)

Upstream product

• 1187943-40-3 1-(4-methoxybenzyl)-2-(2-cyano-2-phenylethyl)aziridine 
• 100-39-0 benzyl bromide 

Relevant articles and documents

A new approach towards 1-phenyl and 1-benzyl substituted 2-(aminomethyl)cyclopropanecarboxamides as novel derivatives of the antidepressant Milnacipran

2-(2-Cyano-2-phenylethyl)aziridines were converted into novel trans-2-aminomethyl-1-phenylcyclopropanecarboxamides via regiospecific ring opening and 3-exo-tet cyclisation, thus providing the first convenient entry into the trans-isomer of Milnacipran as a useful template for further derivatisation. Furthermore, unprecedented 2-aminomethyl-1- benzylcyclopropanecarboxamides have been synthesized using two different routes starting from 2-(2-cyanoethyl)aziridines, both involving α-benzylation with respect to the nitrile group and aziridine to cyclopropane ring transformation. The Royal Society of Chemistry 2009.