1187948-41-9

Upstream product

• 22246-04-4 7-methoxy-3,4-dihydro-2H-isoquinolin-1-one 
• 1187948-37-3 2-isopropyl-7-methoxy-3,4-dihydro-2H-isoquinolin-1-one 
• 91247-71-1 2-4-methoxyphenylethylcarbamic acid methyl ester 
• 55-81-2 4-Methoxyphenethylamine 
• 1187948-39-5 2-isopropyl-7-methoxy-1,2,3,4-tetrahydro-isoquinoline 

Downstream Products

• 1187948-35-1 1-(7-butoxy-2-isopropyl-1,2,3,4-tetrahydro-isoquinolin-4-yl)-cyclohexanol 

Relevant academic research and scientific papers

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

NOVEL MONOAMINE RE-UPTAKE INHIBITOR

The present invention relates to novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers including R and S isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also rel