1187980-73-9

Upstream product

• 91-62-3 6-methylquinoline 
• 106-49-0 p-toluidine 
• 70-11-1 α-bromoacetophenone 
• 101671-01-6 1-nitro-2-(4-chlorophenyl)ethylene 
• 4831-18-9 N-phenacyl-p-toluidine 
• 60532-55-0 1-(4-chloro-phenyl)-2-p-toluidino-ethanone 
• 68-12-2 N,N-dimethyl-formamide 

Relevant academic research and scientific papers

Direct synthesis of 3-arylquinolines by a nano Pd-catalyzed regioselective C3-H arylation of quinolines

3-Arylquinolines are biologically and medicinally very important compounds. Direct and regioselective C3-H arylation offers a straight forward methodology for their synthesis. In this work, we report their synthesis by a Pd nanoparticle catalyzed reaction

Iodine monobromide catalysed regioselective synthesis of 3-arylquinolines from α-aminoacetophenones and: Trans -β-nitrostyrenes

A simple and efficient method for regioselective synthesis of 3-arylquinolines is described from α-aminoacetophenones and trans-β-nitrostyrenes using 20 mol% iodine monobromide as a catalyst in acetonitrile solvent at 80 °C. The present method involves tandem reaction of α-aminoacetophenones and trans-β-nitrostyrenes, formation of two new C-C bonds and cleavage of one C-C bond in a single step. The salient features of the protocol are metal- and oxidant-free reaction conditions, broad substrate scope, and good yields.

A facile and efficient one-pot synthesis of substituted quinolines from α-arylamino ketones under vilsmeier conditions

An efficient: one-pot synthesis of substituted, quinolines from, α-arylamino ketones in the presence of PBr3 in DMF has been developed. This general protocol provides a novel and facile access to substituted quinolines by sequential Vilsmeier-H