1187983-89-6

Upstream product

• 97070-75-2 2-(3-chlorophenyl)-2-hydroxyacetonitrile 
• 24424-99-5 di-tert-butyl dicarbonate 
• 53360-89-7 2-amino-1-(3-chloro-phenyl)-ethanol 
• 587-04-2 m-Chlorobenzaldehyde 

Downstream Products

• 1047630-73-8 [2-amino-2-(3-chloro-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 1387641-32-8 6,7-Dimethoxy-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid [5-[2-amino-1-(3-chloro-phenyl)-ethylcarbamoyl]-2-methyl-phenyl]-amide 
• 1386398-57-7 N-(3-{2-[2-amino-1-(3-chloro-phenyl)-ethylamino]-pyrimidin-4-yl}-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-cyclohexane-1,4-diamine hydrochloride 
• 1386399-50-3 [4-(3-{2-[2-tert-butoxycarbonylamino-1-(3-chloro-phenyl)-ethylamino]-pyrimidin-4-yl}-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)-cyclohexyl]-carbamic acid tert-butyl ester 
• 1400670-19-0 1-(3-chlorophenyl)-N-1-{6-[8-(2-morpholin-4-ylethylamino)imidazo[1,2-a]pyrazin-3-yl]pyridin-2-yl}ethane-1,2-diamine hydrochloride 
• 1400670-07-6 1-(3-chlorophenyl)-N₁-{4-[8-(4-methylpiperazin-1-yl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl}ethane-1,2-diamine hydrochloride 
• 1400670-64-5 (2-(3-chloro-phenyl)-2-{6-[8-(2-morpholin-4-yl-ethylamino)-imidazo[1,2-a]pyrazin-3-yl]-pyridin-2-ylamino}-ethyl)-carbamic acid tert-butyl ester 
• 1400670-54-3 (2-(3-chloro-phenyl)-2-{4-[8-(4-methyl-piperazin-1-yl)-imidazo[1,2-a]pyrazin-3-yl]-pyrimidin-2-ylamino}-ethyl)-carbamic acid tert-butyl ester 
• 1386981-27-6 (S)-2-{4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)amino]benzoylamino}-2-(3-chloro-phenyl-ethyl)carbamic acid tert-butyl ester 
• 1386980-14-8 2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {5-[(S)-2-amino-1-(3-chloro-phenyl)ethylcarbamoyl]-2-chloro-phenyl}amide 
• 1386981-26-5 (R)-2-{4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)amino]benzoylamino}-2-(3-chloro-phenyl-ethyl)carbamic acid tert-butyl ester 
• 1386980-13-7 2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {5-[(R)-2-amino-1-(3-chloro-phenyl)ethylcarbamoyl]-2-chloro-phenyl}amide 
• 1269928-33-7 (S)-tert-butyl (2-amino-2-(3-chlorophenyl)ethyl)carbamate 
• 1269810-89-0 [(R)-2-amino-2-(3-chloro-phenyl)-ethyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

PYRAZOLO PYRIMIDINES

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.

PYRIDO PYRIMIDINES

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.

CARBOXYLIC ACID ARYL AMIDES

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer.

1,6- AND 1,8-NAPHTHYRIDINES

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.

IMIDAZO PYRAZINES

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositio

PYRAZOLO PYRIMIDINES AS DYRK1A AND DYRK1B INHIBITORS

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.