1188-85-8 Usage
Uses
Used in Pharmaceutical Applications:
(-)-2-[(S)-1-O,2-O-Dioctadecyl-D-glycero-3-phospho]ethylamine is used as a nonhydrolizable ether lipid in calcein-containing vesicles for calcein encapsulation.
Used in Scientific Research:
(-)-2-[(S)-1-O,2-O-Dioctadecyl-D-glycero-3-phospho]ethylamine is used to prepare ether-linked phospholipid bilayer membrane for examining its thermotropic and barotropic phase transitions.
Used in Analytical Chemistry:
(-)-2-[(S)-1-O,2-O-Dioctadecyl-D-glycero-3-phospho]ethylamine is used as a component of internal standard mixture for lipid extraction from plasma sample using mass spectrometry.
Check Digit Verification of cas no
The CAS Registry Mumber 1188-85-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1188-85:
(6*1)+(5*1)+(4*8)+(3*8)+(2*8)+(1*5)=88
88 % 10 = 8
So 1188-85-8 is a valid CAS Registry Number.
1188-85-8Relevant academic research and scientific papers
Synthesis of 1,2-Di-O-alkyl-sn-glycero-3-phosphatidylcholine Using 2-Methoxyethoxymethyl and 2-(Trimethylsilyl)ethoxymethyl Protective Groups
Yamauchi, Kiyoshi,Hihara, Mitsuyoshi,Kinoshita, Masayoshi
, p. 2169 - 2172 (2007/10/02)
2-Methoxyethoxymethyl (MEM) and 2-(trimethylsilyl)ethoxymethyl (SEM) groups were used to protect the sn-3-OH of optically active glycerols in the synthesis of 1,2-di-O-octadecyl-sn-glycero-3-phosphatidylcholine.Both MEM and SEM protective groups had advantages of a classical benzyl group by virtue of (i) the facile preparation of 1,2-O-isopropylidene-3-O-(2-methoxyethoxymethyl)-sn-glycerol and its sn-3-O-SEM analog as starting materials and (ii) the rapid demasking of the MEM and SEM moieties in lipid precursors, especially by means of titanium tetrachloride.
