1188-85-8 Usage
Uses
18:0 Diether PC or 1,2-di-O-octadecyl-sn-glycero-3-phosphocholine might be used:as a nonhydrolizable ether lipid in calcein-containing vesicles for calcein encapsulationto prepare ether-linked phospholipid bilayer membrane for examining its thermotropic and barotropic phase transitionsas a component of internal standard mixture for lipid extraction from plasma sample using mass spectromety
General Description
18:0 Diether PC (phosphocholine) is a class of glycerophospholipids that has two octadecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.
Check Digit Verification of cas no
The CAS Registry Mumber 1188-85-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1188-85:
(6*1)+(5*1)+(4*8)+(3*8)+(2*8)+(1*5)=88
88 % 10 = 8
So 1188-85-8 is a valid CAS Registry Number.
1188-85-8Relevant articles and documents
Synthesis of 1,2-Di-O-alkyl-sn-glycero-3-phosphatidylcholine Using 2-Methoxyethoxymethyl and 2-(Trimethylsilyl)ethoxymethyl Protective Groups
Yamauchi, Kiyoshi,Hihara, Mitsuyoshi,Kinoshita, Masayoshi
, p. 2169 - 2172 (2007/10/02)
2-Methoxyethoxymethyl (MEM) and 2-(trimethylsilyl)ethoxymethyl (SEM) groups were used to protect the sn-3-OH of optically active glycerols in the synthesis of 1,2-di-O-octadecyl-sn-glycero-3-phosphatidylcholine.Both MEM and SEM protective groups had advantages of a classical benzyl group by virtue of (i) the facile preparation of 1,2-O-isopropylidene-3-O-(2-methoxyethoxymethyl)-sn-glycerol and its sn-3-O-SEM analog as starting materials and (ii) the rapid demasking of the MEM and SEM moieties in lipid precursors, especially by means of titanium tetrachloride.
