1188301-89-4

Basic information

• Product Name: 5-bromo-2-phenyl-4-(pyridin-4-yl)thiazole
• Synonyms: 5-bromo-2-phenyl-4-(pyridin-4-yl)thiazole
• CAS NO: 1188301-89-4
• Molecular Weight: 317.209
• Mol File: 1188301-89-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-bromo-2-phenyl-4-(pyridin-4-yl)thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-phenyl-4-(pyridin-4-yl)thiazole(1188301-89-4)
• EPA Substance Registry System: 5-bromo-2-phenyl-4-(pyridin-4-yl)thiazole(1188301-89-4)

Safety Data

• Hazardous Substances Data: 1188301-89-4(Hazardous Substances Data)

Upstream product

• 1765-93-1 4-fluoroboronic acid 
• 42409-58-5 5-bromo-3-methoxy-pyridin-2-amine 
• 10201-71-5 3-methoxypyridin-2-amine 
• 20265-37-6 3-methoxy-2-nitropyridine 
• 947249-19-6 3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxoborolan-2-yl)pyridine-2-amine 
• 1142196-38-0 4-bromo-2-(4-fluorophenyl)thiazole 
• 1188301-88-3 2-phenyl-4-(pyridin-4-yl)thiazole 

Downstream Products

• 1450020-21-9 3-methoxy-5-(2-phenyl-4-(pyridine-4-yl)thiazol-5-yl)pyridine-2-amine trifluoroacetate 

Relevant articles and documents

RAF KINASE INHIBITORS

Described herein are compounds, pharmaceutical compositions and methods for the inhibition of RAF kinae mediated signaling. Said compounds, pharmaceutical compositions and methods have utility in the treatment of human disease and disorders.

NOVEL HETEROCYCLIC COMPOUNDS AND USES THEROF

New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.