1188522-91-9

Basic information

• Product Name: 5-BroMo-2'-deoxy-2'-fluoro-3',5'-di-O-acetyl uridine
• Synonyms: 5-bromo-2'-deoxy-2'-fluoro-3',5'-diacetateUridine;5-Bromo-2'-deoxy-2'-fluorouridine 3',5'-diacetate;GXBDBWHTVDEDMG-DNRKLUKYSA-N
• CAS NO: 1188522-91-9
• Molecular Formula: C13H14BrFN2O7
• Molecular Weight: 409.1618632
• Mol File: 1188522-91-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-BroMo-2'-deoxy-2'-fluoro-3',5'-di-O-acetyl uridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BroMo-2'-deoxy-2'-fluoro-3',5'-di-O-acetyl uridine(1188522-91-9)
• EPA Substance Registry System: 5-BroMo-2'-deoxy-2'-fluoro-3',5'-di-O-acetyl uridine(1188522-91-9)

Safety Data

• Hazardous Substances Data: 1188522-91-9(Hazardous Substances Data)

Usage

General Description

5-Bromo-2'-deoxy-2'-fluoro-3',5'-di-O-acetyl uridine is a chemical compound that is a derivative of uridine, a nucleoside found in RNA. 5-BroMo-2'-deoxy-2'-fluoro-3',5'-di-O-acetyl uridine contains bromine, fluorine, and acetyl groups attached to the uridine molecule. It is commonly used in research for its potential therapeutic applications, particularly in the field of antiviral and anticancer drug development. Its chemical structure and properties make it an interesting target for studying its biological effects and potential use in medicine.

Upstream product

• 56287-17-3 2'-deoxy-2'-fluorouridine 
• 10212-13-2 3’,5’-O-acetyl-2’-deoxy-2’-fluorouridine 
• 128-08-5 N-Bromosuccinimide 

Downstream Products

• 1188523-13-8 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-trifluoroacetamido-ethoxy)-1,3-diaza-2-oxophenoxazine 3'-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite 
• 1188523-08-1 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-benzylcarbamyl-ethoxy)-1,3-diaza-2-oxophenoxazine 
• 1188523-11-6 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-trifluoroacetamido-ethoxy)-1,3-diaza-2-oxophenoxazine 
• 1188523-00-3 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-1,3-diaza-2-oxophenoxazine 3'-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite 
• 1178552-81-2 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-trifluoroacetamido-ethoxy)-1,3-diaza-2-oxophenoxazine 
• 1188523-04-7 5-bromo-3',5'-diacetyl-N₄-(2-(2-N-benzylcarbamyl-ethoxy)-6-hydroxyphenyl)-2'-fluoro-2'-deoxycytidine 
• 1174063-99-0 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-1,3-diaza-2-oxophenoxazine 
• 1188523-06-9 3-(2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-benzylcarbamyl-ethoxy)-1,3-diaza-2-oxophenoxazine 
• 1188523-02-5 5-bromo-3',5'-diacetyl-N₄-(2,6-dihydroxyphenyl)-2'-fluoro-2'-deoxycytidine 
• 1188522-96-4 5-bromo-3',5 '-diacetyl-N₄-(2-hydroxyphenyl)-2'-fluoro-2'-deoxycytidine 

Relevant articles and documents

NUCLEIC ACID CHEMICAL MODIFICATIONS

he present invention provides nucleosides of formula (1) and oligonucleotides comprising at least on nucleoside of formula (2): Another aspect of the invention relates to a method of inhibiting the expression of a gene in cell, the method comprising (a) c