1188907-72-3

Upstream product

• 109-01-3 1-methyl-piperazine 
• 1188907-71-2 1-(5-tert-butylisoxazol-3-yl)-3-(3-(7-(3-chloropropoxy)-6-methoxyquinazolin-4-ylthio)phenyl)urea 
• 331809-40-6 4-chloro-7-(3-chloropropoxy)-6-methoxyquinazoline 
• 3943-74-6 4-hydroxy-3-methoxybenzoic acid methyl ester 
• 574738-91-3 7-(3-chloro-propoxy)-6-methoxy-quinazolin-4-ol 
• 111627-40-8 methyl 4-(3-chloropropoxy)-3-methoxybenzoate 
• 214470-59-4 2-Amino-4-(3-chloro-propoxy)-5-methoxy-benzoic acid methyl ester 
• 214470-57-2 methyl 4-(3-chloropropoxy)-5-methoxy-2-nitrobenzoate 

Relevant academic research and scientific papers

QUINAZOLINE DERIVATIVES AS RAF KINASE MODULATORS AND METHODS OF USE THEREOF

Compounds according to formula (I), compositions and methods are provided for modulating the activity of RAF kinases, including BRAF kinase and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder mediated by RAF kinases. Formula (I): or a pharmaceutically acceptable salt, solvate, clathrate of hydrate thereof, wherein X is O or S(O)t; Ra is O or S.