1188932-02-6

Basic information

• Product Name: tert-butyl-N-((R)-6-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-bis(tert-butyldimethylsilyloxy)cyclohexylidene)ethylidene)-7a-methyloctahydro-7H-inden-1-yl)heptyl)sulfamoylcarbamate
• CAS NO: 1188932-02-6
• Molecular Weight: 797.344
• Mol File: 1188932-02-6.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl-N-((R)-6-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-bis(tert-butyldimethylsilyloxy)cyclohexylidene)ethylidene)-7a-methyloctahydro-7H-inden-1-yl)heptyl)sulfamoylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl-N-((R)-6-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-bis(tert-butyldimethylsilyloxy)cyclohexylidene)ethylidene)-7a-methyloctahydro-7H-inden-1-yl)heptyl)sulfamoylcarbamate(1188932-02-6)
• EPA Substance Registry System: tert-butyl-N-((R)-6-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-bis(tert-butyldimethylsilyloxy)cyclohexylidene)ethylidene)-7a-methyloctahydro-7H-inden-1-yl)heptyl)sulfamoylcarbamate(1188932-02-6)

Safety Data

• Hazardous Substances Data: 1188932-02-6(Hazardous Substances Data)

Upstream product

• 1188931-92-1 (R)-6-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-bis(tert-butyldimethylsilyloxy)cyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)heptan-1-amine 
• 352275-00-4 (tert-butoxycarbonyl)-((4-(dimethyliminio)pyridin-1(4H)-yl)sulfonyl)amide 

Downstream Products

• 1188931-76-1 N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-dihydroxycycloheptylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)hexyl)methanesulfamide 

Relevant articles and documents

Vitamin D receptor agonist/histone deacetylase inhibitor molecular hybrids

Incorporation of zinc-binding groups into the side-chain of 1α,25-dihydroxyvitamin D3 (1,25D) fully bifunctional hybrid molecules which act both as vitamin D receptor agonists and histone deacetylase inhibitors. These bifunctional hybrids displ

HYBRID MOLECULES HAVING MIXED VITAMIN D RECEPTOR AGONISM AND HISTONE DEACETYLASE INHIBITORY PROPERTIES

Hybrid molecules comprising a vitamin D receptor agonist moiety and an HDAC inhibitor moiety are described herein. The HDAC inhibitor moiety can be derived from an HDAC inhibitor comprising a functionality selected from the group consisting of an N-hydrox