1189134-15-3 Usage
Description
1-Thio-β-D-glucopyranose 1-Benzenesulfenothioate is a thio-glucose derivative characterized by the presence of a sulfur atom in place of the oxygen atom found in the glycosidic linkage of glucose. This unique structural feature endows it with distinct chemical and biological properties, making it a valuable compound in various applications.
Uses
Used in Biochemical Research:
1-Thio-β-D-glucopyranose 1-Benzenesulfenothioate is used as a reagent in the enzymic elongation of the β(1→3)-glucan chain. Its ability to serve as an alternative substrate for enzymes involved in the synthesis of β(1→3)-glucans makes it a valuable tool for studying the mechanisms and regulation of these complex carbohydrate structures.
Used in Pharmaceutical Development:
As a thio-glucose derivative, 1-Thio-β-D-glucopyranose 1-Benzenesulfenothioate can be employed in the development of novel therapeutic agents targeting carbohydrate-active enzymes or glycosylation pathways. Its unique structure may provide insights into the design of inhibitors or modulators of enzymes involved in the biosynthesis or degradation of β(1→3)-glucans, which are implicated in various diseases and biological processes.
Used in Carbohydrate Chemistry:
1-Thio-β-D-glucopyranose 1-Benzenesulfenothioate can be utilized in the synthesis of various carbohydrate-based compounds, such as oligosaccharides, glycoconjugates, and glycoclusters. Its distinctive sulfur-containing linkage may offer new opportunities for the development of bioactive molecules with potential applications in medicine, biotechnology, and materials science.
Used in Analytical Techniques:
The unique chemical properties of 1-Thio-β-D-glucopyranose 1-Benzenesulfenothioate make it a potentially useful probe in analytical techniques for the detection and characterization of carbohydrates and their interactions with proteins or other biomolecules. Its reactivity and selectivity may be harnessed to develop new methods for the analysis of complex glycans and glycoconjugates in biological samples.
Check Digit Verification of cas no
The CAS Registry Mumber 1189134-15-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,1,3 and 4 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1189134-15:
(9*1)+(8*1)+(7*8)+(6*9)+(5*1)+(4*3)+(3*4)+(2*1)+(1*5)=163
163 % 10 = 3
So 1189134-15-3 is a valid CAS Registry Number.
1189134-15-3Relevant articles and documents
Applications of Shoda's reagent (DMC) and analogues for activation of the anomeric centre of unprotected carbohydrates
Fairbanks, Antony J.
, (2020/12/07)
2-Chloro-1,3-dimethylimidazolinium chloride (DMC, herein also referred to as Shoda's reagent) and its derivatives are useful for numerous synthetic transformations in which the anomeric centre of unprotected reducing sugars is selectively activated in aqueous solution. As such unprotected sugars can undergo anomeric substitution with a range of added nucleophiles, providing highly efficient routes to a range of glycosides and glycoconjugates without the need for traditional protecting group manipulations. This mini-review summarizes the development of DMC and some of its derivatives/analogues, and highlights recent applications for protecting group-free synthesis.
A Chemoenzymatic route to conjugatable β(1→3)-Glucan Oligosaccharides
Montel, Emilie,Hrmova, Maria,Fincher, Geoffrey B.,Driguez, Hugues,Cottaz, Sylvain
experimental part, p. 575 - 584 (2010/01/16)
3II-O-Allyl-α laminaribiosyl fluoride was prepared as a key synthon for the enzymatic synthesis of β(1→3)-glucan oligosaccharides, catalyzed by a mutated β(1→3)-glucanase (E231G) from barley (Hordeum vulgare L.). A strategy was developed for en
