1189138-93-9Relevant articles and documents
Design, synthesis, and biological evaluation of 4-arylmethyl-1- phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists
Yamamoto, Satoshi,Tomita, Naoki,Suzuki, Yuri,Suzaki, Tomohiko,Kaku, Tomohiro,Hara, Takahito,Yamaoka, Masuo,Kanzaki, Naoyuki,Hasuoka, Atsushi,Baba, Atsuo,Ito, Mitsuhiro
, p. 2338 - 2352 (2012/05/07)
A series of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole compounds B were designed, synthesized, and evaluated for their potential as new-generation androgen receptor (AR) antagonists therapeutically effective against castration-resistant