1189140-13-3

Upstream product

• 60702-69-4 2-chloro-4-fluorobenzonitrile 
• 1189140-45-1 2-chloro-4-(4-formyl-3,5-dimethyl-1H-pyrazol-1-yl)-benzonitrile 
• 154606-56-1 2-chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)benzonitrile 

Downstream Products

• 1189140-14-4 4-{4-[(6-aminopyridin-3-yl)oxy]-3,5-dimethyl-1H-pyrazol-1-yl}-2-chlorobenzonitrile 
• 1189140-17-7 N-(5-{[1-(3-chloro-4-cyanophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]oxy}pyridin-2-yl)acetamide 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of 4-arylmethyl-1- phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists

A series of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole compounds B were designed, synthesized, and evaluated for their potential as new-generation androgen receptor (AR) antagonists therapeutically effective against castration-resistant

SUBSTITUTED PYRAZOLE DERIVATIVES AND USE THEREOF

The present invention aims to provide a pyrazole derivative represented by the formula (I') or a salt thereof.