1189152-81-5 Usage
General Description
(S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate is a chemical compound with the molecular formula C14H20BrNO2. It is a pyrrolidine derivative with a tert-butyl ester functional group. (S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate is commonly used in organic chemistry as a building block for the synthesis of various pharmaceuticals and bioactive molecules. It has also been studied for its potential therapeutic applications in the treatment of various medical conditions. The (S)-enantiomer of the compound is known for its specific stereochemical properties and biological activities, making it an important target for research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 1189152-81-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,1,5 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1189152-81:
(9*1)+(8*1)+(7*8)+(6*9)+(5*1)+(4*5)+(3*2)+(2*8)+(1*1)=175
175 % 10 = 5
So 1189152-81-5 is a valid CAS Registry Number.
1189152-81-5Relevant articles and documents
Enantioselective Radical Cyclization for Construction of 5-Membered Ring Structures by Metalloradical C-H Alkylation
Wang, Yong,Wen, Xin,Cui, Xin,Zhang, X. Peter
, p. 4792 - 4796 (2018/04/17)
Radical cyclization represents a powerful strategy for construction of ring structures. Traditional radical cyclization, which is based on radical addition as the key step, necessitates the use of unsaturated substrates. Guided by the concept of metalloradical catalysis, a different mode of radical cyclization that can employ saturated C-H substrates is demonstrated through the development of a Co(II)-based system for catalytic activation of aliphatic diazo compounds for enantioselective radical alkylation of various C(sp3)-H bonds. It allows for efficient construction of chiral pyrrolidines and other valuable 5-membered cyclic compounds. This alternative strategy of radical cyclization provides a new retrosynthetic paradigm to prepare five-membered cyclic molecules from readily available open-chain aldehydes through the union of C-H and C=O elements for C-C bond formation.
