1189154-01-5 Usage
Ester derivative
1-pyrrolidinecarboxylic acid
Also known as
(R)-baclofen
Medical use
Muscle relaxant and antispasmodic agent
Target condition
Muscle spasticity associated with spinal cord injuries and multiple sclerosis
Mechanism of action
Activating GABA receptors in the central nervous system
Effect on neurotransmitters
Suppression of excitatory neurotransmitter release
Additional research
Potential use in the treatment of addiction and various neurological disorders
Check Digit Verification of cas no
The CAS Registry Mumber 1189154-01-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,1,5 and 4 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1189154-01:
(9*1)+(8*1)+(7*8)+(6*9)+(5*1)+(4*5)+(3*4)+(2*0)+(1*1)=165
165 % 10 = 5
So 1189154-01-5 is a valid CAS Registry Number.
1189154-01-5Relevant articles and documents
Highly effective asymmetric hydrogenation of cyclic N -alkyl imines with chiral cationic Ru-MsDPEN catalysts
Chen, Fei,Ding, Ziyuan,Qin, Jie,Wang, Tianli,He, Yanmei,Fan, Qing-Hua
supporting information; experimental part, p. 4348 - 4351 (2011/10/13)
A range of cyclic N-alkyl imines were efficiently hydrogenated by using a chiral cationic Ru(η6-cymene)(MsDPEN)(BArF) complex (MsDPEN = N-(methanesulfonyl)-1,2-diphenylethylenediamine) in high yields and up to 98% ee. A one-pot synthesis of chiral 2-phenylpyrrolidine via reductive amination was also developed.
