1189178-19-5Relevant academic research and scientific papers
Rational design and synthesis of potent dibenzazepine motifs as β-secretase inhibitors
Al-Tel, Taleb H.,Al-Qawasmeh, Raed A.,Schmidt, Marco F.,Al-Aboudi, Amal,Rao, Shashidhar N.,Sabri, Salim S.,Voelter, Wolfgang
supporting information; experimental part, p. 6484 - 6488 (2010/03/31)
We have identified small-molecule dibenzazepine inhibitors of β-secretase (BACE1). These BACE1 inhibitors possess two key salient features. The first is a seven-membered heterocyclic ring fused to two aromatic rings representing the P3-P2 residues. The se
