118919-27-0Relevant academic research and scientific papers
Structure-Antigastrin Activity Relationships of New (R)-4-Benzamido-5-oxopentanoic Acid Derivatives
Makovec, Francesco,Peris, Walter,Revel, Laura,Giovanetti, Roberto,Mennuni, Laura,Rovati, Lucio C.
, p. 28 - 38 (2007/10/02)
New (R)-4-benzamido-5-oxopentanoic acid derivatives were synthesized by a stereoconservative procedure and evaluated in vitro for their capacity to inhibit the binding of (BH)-CCK-8 to either rat peripheral (CCK-A) or central (CCK-B) CCK receptors,
New glutamic and aspartic derivatives with potent CCK-antagonistic activity
Makovec,Chiste,Bani,et al.
, p. 9 - 20 (2007/10/02)
New derivatives of aspartic and glutamic acid were synthesized and evaluated in vitro and in vivo for anti-CCK activity on the guinea pig gallbladder. The anti-CCK activity of some 4-benzamido-glutaramic acid derivatives was a hundred times greater than that of proglutamide, the model compound, and they have been selected for further studies.
