1189353-46-5

Upstream product

• 123-75-1 pyrrolidine 
• 36282-26-5 2-bromo-4-fluorobenzonitrile 

Downstream Products

• 1269407-98-8 2-[(3S)-3-amino-1-pyrrolidinyl]-4-(1-pyrrolidinyl)benzonitrile hydrochloride 
• 1269407-96-6 1,1-dimethylethyl {(3S)-1-[2-cyano-5-(1-pyrrolidinyl)phenyl]-3-pyrrolidinyl}carbamate 

Relevant academic research and scientific papers

CATHEPSIN C INHIBITORS

Disclosed are 3-aminopyrrolidines of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease.

2-ARYL- AND 2-HETEROARYLTHIAZOLYL COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF

The present invention discloses fused bicyclic 2-aryl- or 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumo