1189360-82-4Relevant academic research and scientific papers
Benzodioxane-benzamides as new bacterial cell division inhibitors
Chiodini, Giuseppe,Pallavicini, Marco,Zanotto, Carlo,Bissa, Massimiliano,Radaelli, Antonia,Straniero, Valentina,Bolchi, Cristiano,Fumagalli, Laura,Ruggeri, Paola,De Morghen, Carlo Giuli,Valoti, Ermanno
, p. 252 - 265 (2015/01/08)
A SAR study was performed on 3-substituted 2,6-difluorobenzamides, known inhibitors of the essential bacterial cell division protein FtsZ, through a series of modifications first of 2,6-difluoro-3-nonyloxybenzamide and then of its 3-pyridothiazolylmethoxy analogue PC190723. The study led to the identification of chiral 2,6-difluorobenzamides bearing 1,4-benzodioxane-2-methyl residue at the 3-position as potent antistaphylococcal compounds.
NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS
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Page/Page column 21, (2010/06/22)
The present invention relates to benzodioxane and benzoxazine derivatives that act as ligands for CC chemokine receptors, such as CCR1. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
PROCESS FOR PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES
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Page/Page column 22-23, (2009/10/06)
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparation of intermediat
PROCESS FOR THE PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES
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Page/Page column 51-52, (2009/10/22)
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparation of intermediat
