1189360-81-3Relevant academic research and scientific papers
Benzodioxane-benzamides as new bacterial cell division inhibitors
Chiodini, Giuseppe,Pallavicini, Marco,Zanotto, Carlo,Bissa, Massimiliano,Radaelli, Antonia,Straniero, Valentina,Bolchi, Cristiano,Fumagalli, Laura,Ruggeri, Paola,De Morghen, Carlo Giuli,Valoti, Ermanno
, p. 252 - 265 (2015)
A SAR study was performed on 3-substituted 2,6-difluorobenzamides, known inhibitors of the essential bacterial cell division protein FtsZ, through a series of modifications first of 2,6-difluoro-3-nonyloxybenzamide and then of its 3-pyridothiazolylmethoxy analogue PC190723. The study led to the identification of chiral 2,6-difluorobenzamides bearing 1,4-benzodioxane-2-methyl residue at the 3-position as potent antistaphylococcal compounds.
PROCESS FOR PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES
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Page/Page column 22, (2009/10/06)
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparation of intermediat
PROCESS FOR THE PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES
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Page/Page column 50-51, (2009/10/22)
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparation of intermediat
