1189369-72-9Relevant academic research and scientific papers
Synthesis and in vitro antimicrobial activity of new α- aminophosphonates via tetrazolo [1,5-a] quinoline derivatives
Kategaonkar, Amol H.,Sonar, Swapnil S.,Sapkal, Suryakant B.,Gawali, Vaibhav U.,Shingate, Bapurao B.,Shingare, Murlidhar S.
experimental part, p. 2113 - 2121 (2010/12/18)
A series of diethyl (4-fluorophenylamino) (substituted tetrazolo[1,5-a] quinolin-4-yl)methyl phosphonate derivatives has been synthesized for the first time from tetrazolo [1,5-a] quinoline derivatives. Elemental analysis, IR, 1H NMR, 13C NMR, and mass spectral data elucidated the structures of the all newly synthesized compounds. In vitro antimicrobial activities of synthesized compounds have been investigated against Gram-positive Bacillus subtilis, Gram-negative Escherichia coli, and two fungi Candida albicans and Aspergillus niger in comparison with standard drugs. Significantly, microbiological behavior of these newly synthesized derivatives possesses significant antibacterial and antifungal activity. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright Taylor & Francis Group, LLC.
Synthesis of Schiff s bases of 8-methyl-tetrazolo[1,5-a]quinoline as potential antiinflammatory and antimicrobial agents
Bawa, Sandhya,Kumar, Suresh
experimental part, p. 142 - 145 (2009/12/04)
A series of 4-substituted-imino-methyltetrazolo[1,5-a]quinoline derivatives reported have been synthesized by condensation of 4-formyl-8-methyltetrazolo[1, 5-a]quinoline with appropriate aromatic amine by refluxing in dioxane. All the compounds have been characterized by IR, 1H NMR and mass spectroscopy and have been evaluated for their anti-inflammatory and antimicrobial activities.
