118947-84-5

Upstream product

• 7357-70-2 Cyanothioacetamide 
• 23688-14-4 1-(4-bromo-phenyl)-3-piperidin-1-yl-propenone 
• 53073-03-3 sodium salt of p-bromobenzoylacetaldehyde 
• 14153-75-4 p-bromobenzoylacetaldehyde 

Downstream Products

• 132602-20-1 3-Amino-6-(4-bromo-phenyl)-thieno[2,3-b]pyridine-2-carboxylic acid ethyl ester 
• 128918-20-7 3-Amino-6-(4-brom-phenyl)-thieno<2,3-b>pyridin-2-carbonsaeuredimethylamid 
• 128917-94-2 6-(4-Brom-phenyl)-2-dimethylaminocarbonylmethylthio-pyridin-3-carbonitril 
• 132360-13-5 7-(4-Bromo-phenyl)-2-methyl-pyrido[3',2':4,5]thieno[3,2-d][1,3]oxazin-4-one 
• 128918-21-8 3-Amino-6-(4-bromo-phenyl)-thieno[2,3-b]pyridine-2-carboxylic acid diethylamide 

Relevant academic research and scientific papers

CYCLIZATION REACTIONS OF NITRILS. 29. REGIOSELECTIVE SYNTHESIS OF 6-ARYL-3-CYANO-2(1H)-PYRIDINETHIONES AND THE CORRESPONDING SELENONES AND THEIR CHARACTERISTICS

The condensation of cyanothio- and cyanoselenoacetamide with 3-aryl-3-oxo-1-piperidino-1-propene or sodium 3-aryl-3-oxo-1-propen-1-olate takes place regioselectively with the formation of the 6-aryl-3-cyano-2(1H)-pyridinethiones or the corresponding selenones.Thienopyridines, thiazolopyridinium salts, and other annellated heterocycles were obtained from the 6-aryl-3-cyano-2(1H)-pyridinethiones.