1189552-11-1Relevant academic research and scientific papers
A short and efficient synthesis of licochalcone E
Li, Jizhen,Mi, Yuhua,He, Jianghua,Deng, Xuming
, p. 2289 - 2292 (2010)
Licochalcone E was synthesized concisely via an abnormal Claisen rearrangement and Claisen-Schmidt condensation as the key reactions in a three-step sequence. The overall yield is 20% starting from prenyl bromide and 4-hydroxy-2-methoxybenzaldehyde. Georg
A concise synthesis of licochalcone E and its Regio-isomer, licochalcone F
Na, Younghwa,Cha, Jeong-Heon,Yoon, Ho-Geun,Kwon, Youngjoo
experimental part, p. 607 - 609 (2009/12/09)
Licochalone E is one of the retrochalcones isolated from Glycyrrhiza inflata which shows potent cytotoxicty against human tumor cell lines. Biological studies suggested that topoisomerase I inhibition correlates with cytotoxic properties. Other research r
